Monoclonal antibody (IgG1) Anti-BVDV-1/2 – Target protein E2 (gp53)

Binds to the E2 (gp53) protein of Bovine Viral Diarrhea Virus Type 1 (BVDV-1) and to Bovine Viral Diarrhea Virus Type 2 (BVDV-2). IgG1 isotype. Can be used as a reagent to detect both BVDV-1 and BVDV-2 using indirect immunofluoresence or indirect immunoperoxidase reactions. Does not work with formalin-fixed tissues. This monoclonal antibody is produced as mouse ascites fluid clarified by centrifugation and filtered through a 0.2 micrometer filter. The concentration is 1.0 mg/ml in phosphate-buffered saline preserved with sodium azide. This antibody is stabilized by the addition of 4 mg/ml BSA. Note: BVDV-1 genotypes usually produce only mild diarrhea in immunocompetent cattle while BVDV-2 genotypes can produce thrombocytopenia hemorrhages and acute fatal disease. The viruses of either genotype may exist as one of two biotypes cytopathic or noncytopathic.